Table 1. Macrophages (Raw 264.7 cell line) viabilities of solvent extracts from licorices cultivated in different countries

Extract Cultivar Macrophage viability (%)1)
20 μg/mL 100 μg/mL
Saline2) - 100.0±3.43)
EtOH (E) Jecheon (KJ) 122.2±15.8 130.1±3.1*
China (C) 98.8±4.4 115.3±7.8
Uzbekistan (U) 111.0±8.4 112.9±1.7*
Hot-water (HW) Jecheon (KJ) 145.3±1.3*4) 209.4±13.8*
China (C) 161.6±3.9* 190.2±11.0*
Uzbekistan (U) 152.4±14.6 180.3±6.8*
LPS5) - 193.1±5.8*
Only saline without sample.
Viability (%) = (sample macrophages/saline macrophages) × 100.
Results are presented as mean±standard deviation of four independent experiments.
* p<0.05; significant difference between the saline and each sample.
Lipopolysaccharide (1 μg/mL) from Escherichia coli.