Table 1. Details of clinical trials on drug candidates against COVID-19 (ClinicalTrials.gov)

Intervention/treatment Study type/phase Primary purpose Number of participants
1 Remdesivir Interventional Treatment 453
2 Remdesivir Interventional Treatment 308
3 Remdesivir Expanded access Treatment
4 Remdesivir Interventional Treatment 400
5 Remdesivir Interventional Treatment 600
6 Remdesivir Expanded access Treatment -
7 Remdesivir Interventional Treatment 440
8 Hydroxychloroquine Interventional phase 3 Treatment 440
9 Hydroxychloroquine/remdesivir Interventional Treatment 700
10 Chloroquine/hydroxychloroquine Interventional phase 2 Prevention 55,000
11 Chloroquinephosphate Interventional Treatment 250
12 Chloroquine Interventional phase 2, 3 Treatment 210
13 Chloroquinephosphate Interventional phase 3 Treatment 400
14 Chloroquineor/hydroxychloroquine Interventional Prevention 4,000
15 Chloroquineanalog/nivolumab/tocilizumab Interventional phase 2 Treatment 273
16 Chloroquine/diphosphate Interventional phase 2 Treatment 440
17 Azithromycin/chloroquine Interventional phase 3 Treatment 1,500
18 Azithromycin/hydroxychloroquine Interventional phase 4 Treatment 226
19 Darunavir/hydroxychloroquine Interventional phase 3 Treatment 3,040
20 Hydroxychloroquine Interventional phase 3 Treatment 2,486
21 Hydroxychloroquine Interventional Treatment 220
22 Hydroxychloroquine/azithromycin Interventional phase 3 Treatment 440
23 Hydroxychloroquine Interventional Treatment 1,300
24 Levamisole/budesonide/formoterol, lopinavir/ritonavir/hydroxychloroquine Interventional phase 2, 3 Treatment 30
25 Carrimycin/lopinavir/ritonavir/arbidol chloroquinephosphate Interventional phase 4 Treatment 520
26 Oseltamivir/hydroxychloroquine lopipinavir/ritonavir/darunavir/favipiravir Interventional phase 3 Treatment 80
27 Favipiravir Interventional Treatment 210
28 Favipiravir Interventional phase 3 Treatment 100
29 Arbidol Interventional phase 4 Treatment 380
30 ASC09 (novel investigational protease inhibitor) lopinavir/ritonavir Interventional Treatment 160
31 Lopinavir/ritonavir/hydroxychloroquine Interventional phase 2 Treatment 150
32 Lopinavir/ritonavir Interventional phase 2 Treatment 440
33 Hydroxychloroquine/lopinavir/ritonavir Interventional phase 3 Treatment 1,200
34 Hydroxychloroquine/oseltamivir/azithromycin Interventional phase 3 Treatment 500
35 Lopinavir/ritonavir/hydroxychloroquine Losartan Interventional phase 2,3 Treatment 4,000
36 Abidolhydrochloride/oseltamivir/lopinavir/ritonavir Interventional phase 4 Treatment 400
37 Lopinavir/ritonavir tablets/xiyanping injection Interventional Treatment 80
38 Lopinavir/ritonavir and traditional Chinese medicines Interventional Treatment 150
39 Methylprednisolone Interventional phase 2 Treatment 104
40 Colchicine Interventional phase 3 Treatment 2,500
41 Angiotensin1-7 Interventional phase 2, 3 Treatment 60
42 Thalidomide Interventional phase 2 Treatment 40
43 Thalidomide Interventional phase 2 Treatment 100
44 Dietary supplement:natural honey Interventional phase 3 Treatment 1,000